Greenberg was born in Montreal, Canada, and grew up in a suburb of Detroit. She graduated with honors in 1989 from the Rhode Island School of Design with a BFA in Photography and moved to New York City to pursue a career in photography. Greenberg moved to Los Angeles in 2000 where she met her husband Robert.Greenberg has done commercial work for corporations such as Philip Morris, Microsoft, Compaq, Polaroid, Dreamworks, Sony Pictures, Paramount Pictures, MGM, Disney, Fox, Coca Cola, Pepsi, Smirnoff, MTV, Warner Bros, Sony Music, and Atlantic Records. Her photos have appeared on the covers of Time Magazine, TV Guide, Newsweek, US News and World Report, Wired, Entertainment Weekly and numerous other publications.Her artwork has been featured in Harper’s, The New Yorker, The New Republic and several other publications. Her monkey series has been purchased by art collectors worldwide. She is shown at ClampArt  in New York, and Fahey/Klein in Los Angeles and her artwork has been exhibited in Adelaide, Australia as well as in San Francisco, Chicago, and various other cities.